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Further illuminating matters, operate and therapeutic efficacy of MSCs are highly controlled by the bordering area of interest/microenvironment (Zhu et al., 2016; Mehrbani Azar et al., 2018; Tejero et al., 2019; Gilchrist et al., 2021), and studies on skeletal degenerative and autoimmune disorders have highlighted the essence of mobile-host int
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